Systems glycobiology enabled by innovations in mass spectrometry and chemical biology
Glycosylation is a dominant feature of extracellular phenotypes. Glycoproteins present distinct combinations of glycans and amino acids that create unique molecular surfaces to relay biological information in a language called the glycocode. Despite evidence that the glycocode orchestrates numerous aspects of cell surface biology, we lack a fundamental understanding of the glycosylation landscape across the proteome, largely because we do not have tools to capture the glycocode at a systems level. Our group works to address this critical gap in current analytical technology to study glycocode regulation across biological networks that govern health and disease.
Latest News
2025.01.06
The 2025 Winter Quarter begins!
Good luck to those taking classes and teaching!
2024.12.12
RRG celebrates the end of the quarter with a Holiday Party and gift exchange!
We hope everyone has a great winter break!
2024.12.03
Nick gives a talk in MolES titled "Systems glycobiology through
innovations in mass spectrometry and chemical biology"
2024.11.12
RRG's publication, Autonomous Dissociation-Type Selection
for Glycoproteomics using Real-Time Library Search, has been
accepted to JPR! Congrats Emmajay, Tim, Jacob, and Katie!
2024.11.10 thru 2024.11.13
Nick attends the annual Society of Glycobiology meeting, where he
chairs a session on High-throughput Analytical Approaches for
Characterizing Glycoconjugates and presents a talk on GlyCounter.
2024.11.06
Jacob is featured as a member of UW's first- generation
community. Great to learn about your path here, Jacob!
2024.11.04
Rotation 2 for first-year graduate students in the
Department of Chemistry begins. Welcome rotators!
2024.10.30
Laura has her last day with RRG before she explores the
west coast then heads back to Germany. We will miss you, Laura!
2024.10.15
Nick, Emmajay, and Kayla present talks at the Advances in
Glycoproteomics Analysis Seminar sponsored by TFS.
2024.09.30
Rotation 1 for first-year graduate students in the
Department of Chemistry begins. Welcome rotators!
2024.09.26
Nick gives a seminar at the University of Toronto's
Princess Margaret Cancer Centre.
2024.09.25
The Autumn Quarter 2024 begins!
Nick is teaching CHEM 321, Quantitative Analysis.
See News and Updates for more!
Our Philosophy
We are a lab committed to quality science and a supportive lab environment. Collaboration and mentorship are themes of our group,
and we aim to make sure everyone has the opportunity to pursue their goals in research and beyond.