Systems glycobiology enabled by innovations in mass spectrometry and chemical biology
Glycosylation is a dominant feature of extracellular phenotypes. Glycoproteins present distinct combinations of glycans and amino acids that create unique molecular surfaces to relay biological information in a language called the glycocode. Despite evidence that the glycocode orchestrates numerous aspects of cell surface biology, we lack a fundamental understanding of the glycosylation landscape across the proteome, largely because we do not have tools to capture the glycocode at a systems level. Our group works to address this critical gap in current analytical technology to study glycocode regulation across biological networks that govern health and disease.
Latest News
2024.11.12
RRG's publication, Autonomous Dissociation-Type Selection
for Glycoproteomics using Real-Time Library Search, has been
accepted to JPR! Congrats Emmajay, Tim, Jacob, and Katie!
2024.11.10 thru 2024.11.13
Nick attends the annual Society of Glycobiology meeting, where he
chairs a session on High-throughput Analytical Approaches for
Characterizing Glycoconjugates and presents a talk on GlyCounter.
2024.11.04
Rotation 2 for first-year graduate students in the
Department of Chemistry begins. Welcome rotators!
2024.10.30
Laura has her last day with RRG before she explores the
west coast then heads back to Germany. We will miss you, Laura!
2024.10.15
Nick, Emmajay, and Kayla present talks at the Advances in
Glycoproteomics Analysis Seminar sponsored by TFS.
2024.09.30
Rotation 1 for first-year graduate students in the
Department of Chemistry begins. Welcome rotators!
2024.09.26
Nick gives a seminar at the University of Toronto's
Princess Margaret Cancer Centre.
2024.09.25
The Autumn Quarter 2024 begins!
Nick is teaching CHEM 321, Quantitative Analysis.
2024.09.20
RRG has a new preprint out on ChemRxiv! Revisiting the effect of trypsin
digestion buffers on artificial deamidation. Congrats, Emmajay and Tim!
2024.09.01
RRG was featured by the UW College of
Arts & Sciences, check it out here!
2024.08.30
Daniel has his last day with RRG before heading back to Spain.
We will miss you, Daniel!
2024.08.29
RRG has a new preprint out! Improvements in glycoproteomics
through architecture changes to the Orbitrap Tribrid MS platform
Congrats Tim, Emmajay, Ruby, Kayla, and Anna!
2024.08.26
RRG has a new preprint out! Autonomous Dissociation-Type
Selection for Glycoproteomics using Real-Time Library Search
Congrats Emmajay, Tim, Jacob, and Katie!
2024.08.23
Vishnu has his last day in-person with RRG before beginning
fall courses at UC Berkeley. Good luck this year, Vishnu!
2024.08.20
Meet Assistant Professor Nick Riley was
featured in UW Chemistry Magazine, Autumn 2024 edition!
2024.08.15
Adrian gives a final presentation for the SCROCCS program
and has his last day in the RRG. We enjoyed having you in the
group and will miss you, Adrian. Good luck with your fall
semester back at Pierce College!
2024.08.06
Nick is highlighted in the "Meet the Glycoscientist" section of
the Fall 2024 newsletter from the American Chemical Society
Division of Carbohydrate Chemistry & Chemical Glycobiology (CARB)
2024.07.23
Katie wins first place for her poster at the Cascadia
Proteomics Symposium 2024! Congrats, Katie!
2024.07.23
Jacob and Nick give talks, and Haley gives a flash talk at
the Cascadia Proteomics Symposium 2024!
2024.07.22
Daniel gives a talk and Katie gives a flash talk at
the Cascadia Proteomics Symposium 2024!
2024.07.22 thru 2024.07.23
RRG attends Cascadia Proteomics Symposium 2024
at the Institute for Systems Biology in SLU.
2024.07.01
Anna receives the Member-at-Large Educational Reentry Award given by
the National Honor Society for Women in Chemistry. Congrats, Anna!
See News and Updates for more!
Our Philosophy
We are a lab committed to quality science and a supportive lab environment. Collaboration and mentorship are themes of our group,
and we aim to make sure everyone has the opportunity to pursue their goals in research and beyond.
